Chromosomal abnormalities and « hypoprolificacy »

Epilepsy and chromosomal abnormalities

BACKGROUND Many chromosomal abnormalities are associated with Central Nervous System (CNS) malformations and other neurological alterations, among which seizures and epilepsy. Some of these show a peculiar epileptic and EEG pattern. We describe some epileptic syndromes frequently reported in chromosomal disorders. METHODS Detailed clinical assessment, electrophysiological studies, survey of t...

Association of Fetal and Parental Chromosomal Abnormalities with Congenital Anomalies

Background & Aims: Chromosome abnormalities are a major cause of miscarriage and neonatal mortality. The present study aimed to determine the association of fetal and parents chromosomal abnormalities with congenital anomalies. Methods: A cross-sectional study was performed in a tertiary referral center (Afzalipour Hospital) over 16 months period (2011-2012). The study groups consisted of 77 fe...

Frequency and the Type of Chromosomal Abnormalities in Patients with Primary Amenorrhea in Northeast of Iran

Chromosomal Abnormalities in Reimplantation Development

Direct testing of the outcome of human female meiosis demonstrated that up over a half of oocytes from IVF patients of advanced reproductive age are aneuploid, originating comparably from meiosis I and meiosis II errors, with potential probability of aneuploidy rescue in an almost half of oocytes with sequential first and second meiotic errors. One fifth of abnormalities originating from meiosi...

Screening for Fetal Chromosomal Abnormalities

This Practice Bulletin was developed by the ACOG Committee on Practice Bulletins—Obstetrics, the ACOG Committee on Genetics, and the Society for Maternal–Fetal Medicine Publications Committee with the assistance of Ray Bahado-Singh, MD, and Deborah Driscoll, MD. The information is designed to aid practitioners in making decisions about appropriate obstetric and gynecologic care. These guideline...